The John Bickford House is a historic late First Period house in North Reading, Massachusetts. The c. 1735 two-story timber-frame house has relatively conservative First Period features despite its somewhat (comparatively) late construction date, which may be due to John Bickford's strong connections with nearby Salem. Its timber frame and central chimney are conservative in design, but the building also has Georgian paneling on the interior, and, unusual for the period, a gambrel-style roof.